国際公開番号: WO/2009/113605 国際出願番号: PCT/JP2009/054720
国際公開日: 17.09.2009 国際出願日: 12.03.2009

国際特許分類: A61L 29/00 (2006.01), A61M 25/00 (2006.01)
出願人: AnGes MG, Inc. [JP/JP]; 7-7-15, Saito-Asagi, Ibaraki-shi, Osaka 5670085 (JP) (All Except US).
MEDIKIT CO., LTD. [JP/JP]; 1-13-2, Yushima, Bunkyou-ku, Tokyo, 1130034 (JP) (All Except US).
Hosokawa Micron Corporation [JP/JP]; 1-9, Shoudai-Tajika, Hirakata-shi, Osaka 5731132 (JP) (All Except US).
MORISHITA, Ryuichi [JP/JP]; (JP) (US Only).
NAKAGAMI, Hironori [JP/JP]; (JP) (US Only).
MIYAKE, Takashi [JP/JP]; (JP) (US Only).
MITAMURA, Makoto [JP/JP]; (JP) (US Only).
NAKAJIMA, Hiroaki [JP/JP]; (JP) (US Only).
MATSUDA, Hiroaki [JP/JP]; (JP) (US Only).
SUIZU, Nao [JP/JP]; (JP) (US Only).
KAWANO, Yoshihumi [JP/JP]; (JP) (US Only).
TAKAGI, Kunihiko [JP/JP]; (JP) (US Only).
TSUJIMOTO, Hiroyuki [JP/JP]; (JP) (US Only).
TSUKADA, Yusuke [JP/JP]; (JP) (US Only).
HARA, Kaori [JP/JP]; (JP) (US Only).
BANDO, Yohei [JP/JP]; (JP) (US Only).
発明者: MORISHITA, Ryuichi; (JP).
NAKAGAMI, Hironori; (JP).
MIYAKE, Takashi; (JP).
MITAMURA, Makoto; (JP).
NAKAJIMA, Hiroaki; (JP).
MATSUDA, Hiroaki; (JP).
SUIZU, Nao; (JP).
KAWANO, Yoshihumi; (JP).
TAKAGI, Kunihiko; (JP).
TSUJIMOTO, Hiroyuki; (JP).
TSUKADA, Yusuke; (JP).
HARA, Kaori; (JP).
BANDO, Yohei; (JP).
代理人: SANO, Shizuo; Tenmabashi-Yachiyo Bldg. Bekkan 2-6, Tenmabashi-Kyomachi Chuo-Ku, Osaka-Shi, Osaka 5400032 (JP).
優先権情報: 2008-063143 12.03.2008 JP
2008-249611 29.09.2008 JP

発明の名称: (EN) DRUG ELUTION-TYPE CATHETER AND METHOD FOR MANUFACTURING THE DRUG ELUTION-TYPE CATHETER

(JA) 薬剤溶出型カテーテル及びその製造方法

要約:
(EN) Disclosed is a drug elution-type catheter. In the drug elution-type catheter, biocompatible nanoparticles (1) encapsulating a physiologically active substance and having a surface modified with a positive charge are electrically adhered to a balloon part (9) in a catheter body (5) through a negatively charged resin layer (11) to form a nanoparticle layer (12). After the catheter body (5) is indwelled in a living body, the nanoparticles (1) are gradually eluted from the nanoparticle layer (12) and are efficiently taken into cells.

(JA) 　生理活性物質が封入され表面が正電荷修飾された生体適合性ナノ粒子１を、カテーテル本体５のバルーン部９に負帯電性樹脂層１１を介して電気的に付着させてナノ粒子層１２を形成する。カテーテル本体５を生体内に留置した後、ナノ粒子層１２からナノ粒子１が徐々に溶出して細胞内に効率良く取り込まれる。

指定国: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Org. (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (EAPO) (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (OAPI) (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
国際公開の言語: Japanese (JA)
国際出願の言語: Japanese (JA)